Marco Metra Selected Research

Metoprolol (Toprol-XL)

11/2007	Effect of carvedilol and metoprolol on the mode of death in patients with heart failure.
8/2007	Prognostic importance of plasma NT-pro BNP in chronic heart failure in patients treated with a beta-blocker: results from the Carvedilol Or Metoprolol European Trial (COMET) trial.
8/2007	Effects of metoprolol and carvedilol on pre-existing and new onset diabetes in patients with chronic heart failure: data from the Carvedilol Or Metoprolol European Trial (COMET).
6/2007	The safety of amiodarone in patients with heart failure.
3/2007	Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
4/2006	A comparison of the effects of carvedilol and metoprolol on well-being, morbidity, and mortality (the "patient journey") in patients with heart failure: a report from the Carvedilol Or Metoprolol European Trial (COMET).
12/2005	Rationale and design of the enoximone clinical trials program.
11/2005	Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: results from the COMET trial.
7/2005	Prognostic relevance of atrial fibrillation in patients with chronic heart failure on long-term treatment with beta-blockers: results from COMET.
6/2005	Exchange of beta-blockers in heart failure patients. Experiences from the poststudy phase of COMET (the Carvedilol or Metoprolol European Trial).

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Marco Metra Research Topics

Disease

364	Heart Failure 10/2022 - 02/2002
24	COVID-19 12/2022 - 01/2020
20	Atrial Fibrillation 01/2022 - 07/2005
18	Dyspnea (Shortness of Breath) 01/2019 - 07/2005
17	Renal Insufficiency (Renal Failure) 01/2021 - 01/2007
14	Myocardial Infarction 01/2022 - 04/2002
13	Mitral Valve Insufficiency (Mitral Regurgitation) 08/2022 - 05/2013
13	Inflammation (Inflammations) 11/2021 - 10/2016
13	Heart Diseases (Heart Disease) 03/2021 - 03/2012
12	Hypertension (High Blood Pressure) 10/2021 - 10/2003
11	Stroke (Strokes) 01/2022 - 02/2005
11	Left Ventricular Dysfunction 01/2022 - 05/2003
10	Cardiomyopathies (Cardiomyopathy) 01/2022 - 01/2007
10	Iron Deficiencies 01/2022 - 10/2017
9	Cardiovascular Diseases (Cardiovascular Disease) 06/2022 - 09/2003
9	Hemorrhage 01/2022 - 01/2014
9	Hypotension (Low Blood Pressure) 01/2021 - 02/2002
9	Acute Coronary Syndrome 01/2020 - 08/2007
7	Chronic Renal Insufficiency 01/2022 - 02/2008
7	Weight Loss (Weight Reduction) 01/2022 - 05/2013
7	Type 2 Diabetes Mellitus (MODY) 01/2022 - 04/2012
7	Coronary Artery Disease (Coronary Atherosclerosis) 01/2021 - 04/2002
7	Diabetes Mellitus 01/2021 - 12/2003
6	Infections 06/2022 - 02/2016
6	Thrombosis (Thrombus) 03/2022 - 09/2008
6	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 04/2015
6	Disease Progression 10/2021 - 10/2010
6	Systolic Heart Failure 01/2021 - 07/2003
5	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 05/2013
5	Cardiogenic Shock 12/2021 - 11/2012
5	Edema (Dropsy) 01/2020 - 11/2007
5	Cardio-Renal Syndrome 02/2018 - 09/2005
4	Necrosis 01/2022 - 01/2020
4	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2022 - 02/2009
4	Neoplasms (Cancer) 01/2021 - 11/2018
4	Body Weight (Weight, Body) 01/2019 - 01/2007

Drug/Important Bio-Agent (IBA)

53	Brain Natriuretic Peptide (Natrecor)FDA Link 06/2022 - 12/2003
47	Biomarkers (Surrogate Marker)IBA 06/2022 - 08/2007
23	pro-brain natriuretic peptide (1-76)IBA 04/2022 - 08/2007
19	TroponinIBA 12/2022 - 08/2007
19	DiureticsIBA 01/2022 - 07/2003
19	rolofyllineIBA 11/2019 - 10/2008
18	Carvedilol (Coreg)FDA LinkGeneric 02/2010 - 02/2002
17	CreatinineIBA 01/2022 - 01/2012
17	Metoprolol (Toprol-XL)FDA LinkGeneric 11/2007 - 02/2002
16	Natriuretic PeptidesIBA 03/2022 - 09/2003
16	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 06/2021 - 05/2003
13	Pharmaceutical PreparationsIBA 10/2022 - 01/2010
13	Mineralocorticoid Receptor AntagonistsIBA 07/2022 - 09/2004
13	RelaxinIBA 12/2021 - 04/2009
12	SodiumIBA 01/2022 - 05/2013
11	Urea (Carbamide)FDA LinkGeneric 01/2017 - 01/2014
10	omecamtiv mecarbilIBA 05/2022 - 03/2016
10	sacubitril and valsartan sodium hydrate drug combinationIBA 04/2022 - 09/2018
10	Angiotensin Receptor AntagonistsIBA 06/2021 - 09/2004
10	Purinergic P1 Receptor AntagonistsIBA 11/2019 - 01/2010
9	ferric carboxymaltoseIBA 01/2022 - 10/2017
9	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 08/2007
9	NitrogenIBA 01/2017 - 01/2014
8	AnticoagulantsIBA 03/2022 - 09/2008
8	PotassiumIBA 01/2022 - 09/2015
8	Troponin T (Troponin T1)IBA 11/2020 - 08/2007
7	Furosemide (Lasix)FDA LinkGeneric 01/2022 - 02/2008
7	Interleukin-6 (Interleukin 6)IBA 01/2022 - 01/2011
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2011
7	Cardiac MyosinsIBA 01/2022 - 03/2016
7	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 01/2022 - 11/2014
6	ReninIBA 03/2022 - 09/2003
6	AldosteroneIBA 03/2022 - 09/2003
6	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2022 - 01/2020
6	IvabradineIBA 11/2021 - 08/2013
6	Adenosine (Adenocard)FDA LinkGeneric 03/2012 - 10/2008
5	AngiotensinsIBA 03/2022 - 01/2007
5	Enalapril FDA LinkGeneric 03/2022 - 10/2017
5	IronIBA 01/2022 - 10/2017
5	Growth Differentiation Factor 15IBA 01/2022 - 11/2015
5	empagliflozinIBA 01/2022 - 10/2019
5	LigandsIBA 01/2022 - 01/2007
5	Endothelin-1 (Endothelin 1)IBA 12/2020 - 07/2005
5	Hemoglobins (Hemoglobin)IBA 12/2018 - 05/2013
5	Endothelin Receptors (Endothelin Receptor)IBA 01/2017 - 07/2005
4	CarbohydratesIBA 04/2022 - 05/2003
4	Neprilysin (Neutral Endopeptidase)IBA 03/2022 - 10/2017
4	SymportersIBA 01/2022 - 10/2019
4	Sodium-Glucose Transport ProteinsIBA 01/2022 - 01/2021
4	Warfarin (Coumadin)FDA LinkGeneric 01/2022 - 05/2003
4	CytokinesIBA 01/2021 - 02/2009
4	Ferritins (Ferritin)IBA 12/2020 - 12/2018
4	C-Reactive ProteinIBA 07/2020 - 01/2011
4	Carbon DioxideIBA 01/2020 - 08/2006
4	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 11/2019 - 10/2017

Therapy/Procedure

132	Therapeutics 08/2022 - 02/2002
38	Patient Readmission 01/2022 - 01/2010
16	Length of Stay 12/2020 - 01/2010
10	Cardiac Resynchronization Therapy 01/2019 - 01/2007
8	Heart Transplantation (Grafting, Heart) 11/2021 - 04/2002
4	Palliative Care (Palliative Therapy) 01/2022 - 12/2005
4	Transcatheter Aortic Valve Replacement 01/2022 - 09/2014
4	Critical Care (Surgical Intensive Care) 01/2021 - 05/2010
4	Percutaneous Coronary Intervention 11/2020 - 04/2012